Yeast Mpo1 Is a Novel Dioxygenase That Catalyzes the α

mpo12-hydroxy-palmitic acid dioxygenase Mpo1-like Budding yeast Mpo1 is a dioxygenase that catalyzes the alpha-oxidation of a 2-hydroxy fatty acid in an Fe2+-dependentOur findings indicate that Mpo1 catalyzes the FA α-oxidation reaction as 2-OH fatty acid dioxygenase, mediated by iron(IV) peroxide. Although numerous Mpo1 homologs exist in